Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

Cubilin is a 460-kDa protein functioning as an endocytic receptor for intrinsic factor vitamin B(12) complex in the intestine and as a receptor for apolipoprotein A1 and albumin reabsorption in the kidney proximal tubules and the yolk sac. In the present study, we report the identification of cubili...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kozyraki, Renata, Fyfe, John, Verroust, Pierre J., Jacobsen, Christian, Dautry-Varsat, Alice, Gburek, Jakub, Willnow, Thomas E., Christensen, Erik Ilsø, Moestrup, Søren K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211291398
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