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Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule
Cadmium (Cd(2+)) in the environment is a significant health hazard. Chronic low Cd(2+) exposure mainly results from food and tobacco smoking and causes kidney damage, predominantly in the proximal tubule. Blood Cd(2+) binds to thiol-containing high (e.g., albumin, transferrin) and low molecular weig...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6566203/ https://ncbi.nlm.nih.gov/pubmed/31091675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102379 |
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