Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule

Cadmium (Cd(2+)) in the environment is a significant health hazard. Chronic low Cd(2+) exposure mainly results from food and tobacco smoking and causes kidney damage, predominantly in the proximal tubule. Blood Cd(2+) binds to thiol-containing high (e.g., albumin, transferrin) and low molecular weig...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Fels, Johannes, Scharner, Bettina, Zarbock, Ralf, Zavala Guevara, Itzel Pamela, Lee, Wing-Kee, Barbier, Olivier C., Thévenod, Frank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566203/
https://ncbi.nlm.nih.gov/pubmed/31091675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102379
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller