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Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs

Alphaviruses are arthropod-transmitted RNA viruses that can cause arthralgia, myalgia, and encephalitis in humans. Since the role of cellular kinases in alphavirus replication is unknown, we profiled kinetic changes in host kinase abundance and phosphorylation following chikungunya virus (CHIKV) inf...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Broeckel, Rebecca, Sarkar, Sanjay, May, Nicholas A., Totonchy, Jennifer, Kreklywich, Craig N., Smith, Patricia, Graves, Lee, DeFilippis, Victor R., Heise, Mark T., Morrison, Thomas E., Moorman, Nathaniel, Streblow, Daniel N.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496153/
https://ncbi.nlm.nih.gov/pubmed/30917980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02325-18
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