Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs

Alphaviruses are arthropod-transmitted RNA viruses that can cause arthralgia, myalgia, and encephalitis in humans. Since the role of cellular kinases in alphavirus replication is unknown, we profiled kinetic changes in host kinase abundance and phosphorylation following chikungunya virus (CHIKV) inf...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Broeckel, Rebecca, Sarkar, Sanjay, May, Nicholas A., Totonchy, Jennifer, Kreklywich, Craig N., Smith, Patricia, Graves, Lee, DeFilippis, Victor R., Heise, Mark T., Morrison, Thomas E., Moorman, Nathaniel, Streblow, Daniel N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496153/
https://ncbi.nlm.nih.gov/pubmed/30917980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02325-18
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