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Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry

Proteolysis is an integral component of life and has been implicated in many disease processes. To improve our understanding of peptidase function, it is imperative to develop tools to uncover substrate specificity and cleavage efficiency. Here, we combine the quantitative power of tandem mass tags...

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Bibliografski detalji
Izdano u:Mol Cell Proteomics
Glavni autori: Lapek, John D., Jiang, Zhenze, Wozniak, Jacob M., Arutyunova, Elena, Wang, Steven C, Lemieux, M. Joanne, Gonzalez, David J., O'Donoghue, Anthony J.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495252/
https://ncbi.nlm.nih.gov/pubmed/30705125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001099
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