Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry

Proteolysis is an integral component of life and has been implicated in many disease processes. To improve our understanding of peptidase function, it is imperative to develop tools to uncover substrate specificity and cleavage efficiency. Here, we combine the quantitative power of tandem mass tags...

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Sparad:
Bibliografiska uppgifter
I publikationen:Mol Cell Proteomics
Huvudupphovsmän: Lapek, John D., Jiang, Zhenze, Wozniak, Jacob M., Arutyunova, Elena, Wang, Steven C, Lemieux, M. Joanne, Gonzalez, David J., O'Donoghue, Anthony J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Technological Innovation and Resources
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495252/
https://ncbi.nlm.nih.gov/pubmed/30705125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001099
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