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Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry

Proteolysis is an integral component of life and has been implicated in many disease processes. To improve our understanding of peptidase function, it is imperative to develop tools to uncover substrate specificity and cleavage efficiency. Here, we combine the quantitative power of tandem mass tags...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Lapek, John D., Jiang, Zhenze, Wozniak, Jacob M., Arutyunova, Elena, Wang, Steven C, Lemieux, M. Joanne, Gonzalez, David J., O'Donoghue, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495252/
https://ncbi.nlm.nih.gov/pubmed/30705125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001099
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