Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry

Proteolysis is an integral component of life and has been implicated in many disease processes. To improve our understanding of peptidase function, it is imperative to develop tools to uncover substrate specificity and cleavage efficiency. Here, we combine the quantitative power of tandem mass tags...

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Библиографические подробности
Опубликовано в: :Mol Cell Proteomics
Главные авторы: Lapek, John D., Jiang, Zhenze, Wozniak, Jacob M., Arutyunova, Elena, Wang, Steven C, Lemieux, M. Joanne, Gonzalez, David J., O'Donoghue, Anthony J.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2019
Предметы:
Technological Innovation and Resources
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495252/
https://ncbi.nlm.nih.gov/pubmed/30705125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001099
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