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Global Identification of Peptidase Specificity by Multiplex Substrate Profiling
A simple and rapid multiplex substrate profiling method has been developed to reveal the substrate specificity of any endo- or exo-peptidase using LC-MS/MS sequencing. A physicochemically diverse library of peptides was generated by incorporating all combinations of neighbor and near-neighbor amino...
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| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707110/ https://ncbi.nlm.nih.gov/pubmed/23023596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2182 |
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