Global Identification of Peptidase Specificity by Multiplex Substrate Profiling

A simple and rapid multiplex substrate profiling method has been developed to reveal the substrate specificity of any endo- or exo-peptidase using LC-MS/MS sequencing. A physicochemically diverse library of peptides was generated by incorporating all combinations of neighbor and near-neighbor amino...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: O’Donoghue, Anthony J., Eroy-Reveles, A. Alegra, Knudsen, Giselle M., Ingram, Jessica, Zhou, Min, Statnekov, Jacob B., Greninger, Alexander L., Hostetter, Daniel R., Qu, Gang, Maltby, David A., Anderson, Marc O., DeRisi, Joseph L., McKerrow, James H., Burlingame, Alma L., Craik, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707110/
https://ncbi.nlm.nih.gov/pubmed/23023596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2182
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados