Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models

In combination cancer immunotherapies, consideration should be given to designing treatment schedules that harmonize with the immune system’s natural timing. An efficacious temporally programmed combination therapy of extended half-life interleukin 2 (eIL2), tumor targeting antibody, and interferon...

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Bibliografische gegevens
Gepubliceerd in:Oncoimmunology
Hoofdauteurs: Rothschilds, Adrienne, Tzeng, Alice, Mehta, Naveen K., Moynihan, Kelly D., Irvine, Darrell J., Wittrup, K. Dane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492973/
https://ncbi.nlm.nih.gov/pubmed/31069130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1558678
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