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Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models

In combination cancer immunotherapies, consideration should be given to designing treatment schedules that harmonize with the immune system’s natural timing. An efficacious temporally programmed combination therapy of extended half-life interleukin 2 (eIL2), tumor targeting antibody, and interferon...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Rothschilds, Adrienne, Tzeng, Alice, Mehta, Naveen K., Moynihan, Kelly D., Irvine, Darrell J., Wittrup, K. Dane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492973/
https://ncbi.nlm.nih.gov/pubmed/31069130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1558678
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