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Temporally Programmed CD8α(+) DC Activation Enhances Combination Cancer Immunotherapy

Numerous synergistic cancer immunotherapy combinations have been identified, but the effects of relative dose timing are rarely considered. In established syngeneic mouse tumor models, we found that staggering IFNα administration after, rather than before or simultaneously with, serum-persistent IL-...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Tzeng, Alice, Kauke, Monique J., Zhu, Eric F., Moynihan, Kelly D., Opel, Cary F., Yang, Nicole J., Mehta, Naveen, Kelly, Ryan L., Szeto, Gregory L., Overwijk, Willem W., Irvine, Darrell J., Wittrup, K. Dane
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204262/
https://ncbi.nlm.nih.gov/pubmed/27926855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.020
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