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Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice

Following curative immunotherapy of B16F10 tumors, ~60% of mice develop a strong antibody response against cell-surface tumor antigens. Their antisera confer prophylactic protection against intravenous challenge with B16F10 cells, and also cross-react with syngeneic and allogeneic tumor cell lines M...

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Foilsithe in:PLoS One
Main Authors: Kang, Byong H., Momin, Noor, Moynihan, Kelly D., Silva, Murillo, Li, Yingzhong, Irvine, Darrell J., Wittrup, K. Dane
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049297/
https://ncbi.nlm.nih.gov/pubmed/33857179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248903
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