Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy

The clinical application of cytokine therapies for cancer treatment remains limited due to severe adverse reactions and insufficient therapeutic effects. Although cytokine localization by intratumoral administration could address both issues, the rapid escape of soluble cytokines from the tumor inva...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Momin, Noor, Mehta, Naveen K., Bennett, Nitasha R., Ma, Leyuan, Palmeri, Joseph R., Chinn, Magnolia M., Lutz, Emi A., Kang, Byong, Irvine, Darrell J., Spranger, Stefani, Wittrup, K. Dane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811803/
https://ncbi.nlm.nih.gov/pubmed/31243150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw2614
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