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Dose Dependence of Intratumoral Perivascular Distribution of Monoclonal Antibodies

Intravenously delivered antibodies have been previously found to distribute in a perivascular fashion in a variety of tumor types and despite targeting a range of different antigens. Properties of both the antibody and the targeted antigen, such as the administered dose, binding affinity, and antige...

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Detalhes bibliográficos
Main Authors: Rhoden, John J., Wittrup, Karl Dane
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971539/
https://ncbi.nlm.nih.gov/pubmed/22057714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22801
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