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Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models

In combination cancer immunotherapies, consideration should be given to designing treatment schedules that harmonize with the immune system’s natural timing. An efficacious temporally programmed combination therapy of extended half-life interleukin 2 (eIL2), tumor targeting antibody, and interferon...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Rothschilds, Adrienne, Tzeng, Alice, Mehta, Naveen K., Moynihan, Kelly D., Irvine, Darrell J., Wittrup, K. Dane
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492973/
https://ncbi.nlm.nih.gov/pubmed/31069130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1558678
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