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Pharmacokinetic tuning of protein-antigen fusions to enhance the potency of therapeutic T cell vaccines
Recent advances in immuno-oncology have generated renewed optimism for therapeutic anti-tumor vaccination, and peptide vaccines in particular are being extensively employed in clinical studies. However, peptide vaccines generally suffer from poor immunogenicity. Here, we pharmacokinetically tune vac...
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| Udgivet i: | Nat Biomed Eng |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575059/ https://ncbi.nlm.nih.gov/pubmed/32483299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0563-4 |
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