Temporally Programmed CD8α(+) DC Activation Enhances Combination Cancer Immunotherapy

Numerous synergistic cancer immunotherapy combinations have been identified, but the effects of relative dose timing are rarely considered. In established syngeneic mouse tumor models, we found that staggering IFNα administration after, rather than before or simultaneously with, serum-persistent IL-...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Tzeng, Alice, Kauke, Monique J., Zhu, Eric F., Moynihan, Kelly D., Opel, Cary F., Yang, Nicole J., Mehta, Naveen, Kelly, Ryan L., Szeto, Gregory L., Overwijk, Willem W., Irvine, Darrell J., Wittrup, K. Dane
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204262/
https://ncbi.nlm.nih.gov/pubmed/27926855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.020
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