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Synthesis and Biological Evaluation of Solithromycin Analogs Against Multidrug Resistant Pathogens
Novel antibacterial drugs that treat multidrug resistant pathogens are in high demand. We have synthesized analogs of solithromycin using Cu(I)-mediated click chemistry. Evaluation of the analogs using Minimum Inhibitory Concentration (MIC) assays against resistant Staphylococcus aureus, Escherichia...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487207/ https://ncbi.nlm.nih.gov/pubmed/30962084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.03.038 |
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