Synthesis and Biological Evaluation of Solithromycin Analogs Against Multidrug Resistant Pathogens

Novel antibacterial drugs that treat multidrug resistant pathogens are in high demand. We have synthesized analogs of solithromycin using Cu(I)-mediated click chemistry. Evaluation of the analogs using Minimum Inhibitory Concentration (MIC) assays against resistant Staphylococcus aureus, Escherichia...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem Lett
Hoofdauteurs: Daher, Samer S., Jin, Xiao, Patel, Jimmy, Freundlich, Joel S., Buttaro, Bettina, Andrade, Rodrigo B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487207/
https://ncbi.nlm.nih.gov/pubmed/30962084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.03.038
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items