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Synthesis and biological evaluation of semi-synthetic albocycline analogs
Albocycline (ALB) is a unique macrolactone natural product with potent, narrow-spectrum activity against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate (VISA), and vancomycin-resistant S. aureus (VRSA) strains (MIC = 0.5–1.0 μg/mL). Described herein is the synthesis and...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577960/ https://ncbi.nlm.nih.gov/pubmed/32827630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127509 |
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