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δ-Carbolines and their ring-opened analogs: Synthesis and evaluation against fungal and bacterial opportunistic pathogens

Previous studies have indicated that the δ-carboline (2) ring system derived from the natural product cryptolepine (1) may represent a pharmacophore for anti-infective activity. This paper describes the design and synthesis of a small library of substituted δ-carbolines and the evaluation of the ant...

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Detalhes bibliográficos
Main Authors: Mazu, Tryphon K., Etukala, Jagan R., Jacob, Melissa R., Khan, Shabana I., Walker, Larry A., Ablordeppey, Seth Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130796/
https://ncbi.nlm.nih.gov/pubmed/21459492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.03.021
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