Structure-Activity Relationship (SAR) and Preliminary Mode of Action Studies of 3-Substituted Benzylthioquinolinium Iodide as Anti-opportunistic Infection Agents

Opportunistic infections are devastating to immunocompromised patients. And in especially sub-Saharan Africa where the AIDS epidemic is still raging, the mortality rate was recently as high as 70%. The paucity of anti-opportunistic drugs, the decreasing efficacy and the development of resistance aga...

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Detalhes bibliográficos
Main Authors: Bolden, Sidney, Zhu, Xue Y., Etukala, Jagan R, Boateng, Comfort, Mazu, Tryphon, Flores-Rozas, Hernan, Jacob, Melissa R., Khan, Shabana I, Walker, Larry A., Ablordeppey, Seth Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870201/
https://ncbi.nlm.nih.gov/pubmed/24141203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.09.044
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