SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury

Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial dysfunction and inflammation in ALI is not well understood. In this report, we demonstrate a critical role for the mitochondrial NAD(+)-dependent dea...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Kurundkar, Deepali, Kurundkar, Ashish R., Bone, Nathaniel B., Becker, Eugene J., Liu, Wanqu, Chacko, Balu, Darley-Usmar, Victor, Zmijewski, Jaroslaw W., Thannickal, Victor J.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485358/
https://ncbi.nlm.nih.gov/pubmed/30626741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120722
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