SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury

Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial dysfunction and inflammation in ALI is not well understood. In this report, we demonstrate a critical role for the mitochondrial NAD(+)-dependent dea...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Kurundkar, Deepali, Kurundkar, Ashish R., Bone, Nathaniel B., Becker, Eugene J., Liu, Wanqu, Chacko, Balu, Darley-Usmar, Victor, Zmijewski, Jaroslaw W., Thannickal, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485358/
https://ncbi.nlm.nih.gov/pubmed/30626741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120722
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