SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury

Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial dysfunction and inflammation in ALI is not well understood. In this report, we demonstrate a critical role for the mitochondrial NAD(+)-dependent dea...

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Библиографические подробности
Опубликовано в: :JCI Insight
Главные авторы: Kurundkar, Deepali, Kurundkar, Ashish R., Bone, Nathaniel B., Becker, Eugene J., Liu, Wanqu, Chacko, Balu, Darley-Usmar, Victor, Zmijewski, Jaroslaw W., Thannickal, Victor J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485358/
https://ncbi.nlm.nih.gov/pubmed/30626741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120722
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