SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury

Acute lung injury (ALI) is characterized by exuberant proinflammatory responses and mitochondrial dysfunction. However, the link between mitochondrial dysfunction and inflammation in ALI is not well understood. In this report, we demonstrate a critical role for the mitochondrial NAD(+)-dependent dea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Kurundkar, Deepali, Kurundkar, Ashish R., Bone, Nathaniel B., Becker, Eugene J., Liu, Wanqu, Chacko, Balu, Darley-Usmar, Victor, Zmijewski, Jaroslaw W., Thannickal, Victor J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485358/
https://ncbi.nlm.nih.gov/pubmed/30626741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120722
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