Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis

Cytotoxic T lymphocyte (CTL) activation contributes to liver damage during sepsis, but the mechanisms involved are largely unknown. Understanding the underlying principle will permit interference with CTL activation and thus, provide a new therapeutic option. Methods: To elucidate the mechanism lead...

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Detaylı Bibliyografya
Yayımlandı:Theranostics
Asıl Yazarlar: von Knethen, Andreas, Schäfer, Anne, Kuchler, Laura, Knape, Tilo, Christen, Urs, Hintermann, Edith, Fißlthaler, Beate, Schröder, Katrin, Brandes, Ralf P., Genz, Berit, Abshagen, Kerstin, Pützer, Brigitte M., Sha, Lisa K., Weigert, Andreas, Syed, Shahzad N., Schulz, Martin, Shah, Ajay M., Ernst, Andreas, Putyrski, Mateusz, Finkelmeier, Fabian, Pesic, Marina, Greten, Florian, Hogardt, Michael, Kempf, Volkhard A. J., Gunne, Sandra, Parnham, Michael J., Brüne, Bernhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485280/
https://ncbi.nlm.nih.gov/pubmed/31037153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.28057
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