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Apoptotic regress of immature single positive and double positive thymocyte subpopulations contributes to thymus involution during murine polymicrobial sepsis

In order to generate and maintain a functional T cell receptor diversity, thymocyte development has to be a tightly organized process. Errors can have dramatic consequences, leading to, for instance, autoimmune diseases. Probably for this reason the thymus reacts to stressors like sepsis with involu...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Netzer, Christoph, Knape, Tilo, Kuchler, Laura, Weigert, Andreas, Zacharowski, Kai, Pfeilschifter, Waltraud, Sempowski, Gregory, Brüne, Bernhard, von Knethen, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263038/
https://ncbi.nlm.nih.gov/pubmed/28708784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000842
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