Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells

PPARγ is a pharmacological target in inflammatory and metabolic diseases. Upon agonistic treatment or following antagonism, binding of co-factors is altered, which consequently affects PPARγ-dependent transactivation as well as its DNA-independent properties. Therefore, establishing techniques to ch...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Trümper, Verena, von Knethen, Andreas, Preuß, Annegret, Ermilov, Eugeny, Hackbarth, Steffen, Kuchler, Laura, Gunne, Sandra, Schäfer, Anne, Bornhütter, Tobias, Vereb, György, Ujlaky-Nagy, Lázló, Brüne, Bernhard, Röder, Beate, Schindler, Michael, Parnham, Michael J., Knape, Tilo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735382/
https://ncbi.nlm.nih.gov/pubmed/31534496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29367
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