Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis

Cytotoxic T lymphocyte (CTL) activation contributes to liver damage during sepsis, but the mechanisms involved are largely unknown. Understanding the underlying principle will permit interference with CTL activation and thus, provide a new therapeutic option. Methods: To elucidate the mechanism lead...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: von Knethen, Andreas, Schäfer, Anne, Kuchler, Laura, Knape, Tilo, Christen, Urs, Hintermann, Edith, Fißlthaler, Beate, Schröder, Katrin, Brandes, Ralf P., Genz, Berit, Abshagen, Kerstin, Pützer, Brigitte M., Sha, Lisa K., Weigert, Andreas, Syed, Shahzad N., Schulz, Martin, Shah, Ajay M., Ernst, Andreas, Putyrski, Mateusz, Finkelmeier, Fabian, Pesic, Marina, Greten, Florian, Hogardt, Michael, Kempf, Volkhard A. J., Gunne, Sandra, Parnham, Michael J., Brüne, Bernhard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2019
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485280/
https://ncbi.nlm.nih.gov/pubmed/31037153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.28057
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