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Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases
The proteasome holoenzyme is a molecular machine that degrades most proteins in eukaryotes. In the holoenzyme, its heterohexameric ATPase injects protein substrates into the proteolytic core particle, where degradation occurs. The heterohexameric ATPase, referred to as 'Rpt ring', assemble...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484131/ https://ncbi.nlm.nih.gov/pubmed/30814255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006298 |
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