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ATP Binding by Proteasomal ATPases Regulates Cellular Assembly and Substrate-induced Functions of the 26 S Proteasome

We examined the role of ATP binding by six different ATPase subunits (Rpt1–6) in the cellular assembly and molecular functions of mammalian 26 S proteasome. Four Rpt subunits (Rpt1–4) with ATP binding mutations were incompetent for cellular assembly into 26 S proteasome. In contrast, analogous mutan...

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Detalhes bibliográficos
Main Authors: Kim, Young-Chan, Li, Xiaohua, Thompson, David, DeMartino, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561553/
https://ncbi.nlm.nih.gov/pubmed/23212908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424788
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