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VARIABLY MODULATED GATING OF THE 26S PROTEASOME BY ATP AND POLYUBIQUITIN

The 26S proteasome is a 2,500,000-dalton protease complex that degrades polyubiquitylated proteins by a mechanism that requires ATP hydrolysis. It also degrades short non-ubiquitylated peptides and certain unstructured proteins by an energy-independent mechanism that requires bound ATP to maintain i...

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Detalhes bibliográficos
Main Authors: Li, Xiaohua, DeMartino, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872633/
https://ncbi.nlm.nih.gov/pubmed/19435460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090528
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