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VARIABLY MODULATED GATING OF THE 26S PROTEASOME BY ATP AND POLYUBIQUITIN
The 26S proteasome is a 2,500,000-dalton protease complex that degrades polyubiquitylated proteins by a mechanism that requires ATP hydrolysis. It also degrades short non-ubiquitylated peptides and certain unstructured proteins by an energy-independent mechanism that requires bound ATP to maintain i...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872633/ https://ncbi.nlm.nih.gov/pubmed/19435460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090528 |
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