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VARIABLY MODULATED GATING OF THE 26S PROTEASOME BY ATP AND POLYUBIQUITIN
The 26S proteasome is a 2,500,000-dalton protease complex that degrades polyubiquitylated proteins by a mechanism that requires ATP hydrolysis. It also degrades short non-ubiquitylated peptides and certain unstructured proteins by an energy-independent mechanism that requires bound ATP to maintain i...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872633/ https://ncbi.nlm.nih.gov/pubmed/19435460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090528 |
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