ATP Binding and ATP Hydrolysis Play Distinct Roles in the Function of 26S Proteasome

The 26S proteasome degrades polyubiquitinated proteins by an energy-dependent mechanism. Here we define multiple roles for ATP in 26S proteasome function. ATP binding is necessary and sufficient for assembly of 26S proteasome from 20S proteasome and PA700/19S subcomplexes and for proteasome activati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Liu, Chang-Wei, Li, Xiaohua, Thompson, David, Wooding, Kerry, Chang, Tsui-ling, Tang, Zhanyun, Yu, Hongtao, Thomas, Philip J., DeMartino, George N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951175/
https://ncbi.nlm.nih.gov/pubmed/17018291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.08.025
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia