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Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases

The proteasome holoenzyme is a molecular machine that degrades most proteins in eukaryotes. In the holoenzyme, its heterohexameric ATPase injects protein substrates into the proteolytic core particle, where degradation occurs. The heterohexameric ATPase, referred to as 'Rpt ring', assemble...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Nahar, Asrafun, Fu, Xinyi, Polovin, George, Orth, James D., Park, Soyeon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484131/
https://ncbi.nlm.nih.gov/pubmed/30814255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006298
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