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Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases

The proteasome holoenzyme is a molecular machine that degrades most proteins in eukaryotes. In the holoenzyme, its heterohexameric ATPase injects protein substrates into the proteolytic core particle, where degradation occurs. The heterohexameric ATPase, referred to as 'Rpt ring', assemble...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Nahar, Asrafun, Fu, Xinyi, Polovin, George, Orth, James D., Park, Soyeon
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484131/
https://ncbi.nlm.nih.gov/pubmed/30814255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006298
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