Structure-Based Virtual Screening and In Vitro Evaluation of New Trypanosoma cruzi Cruzain Inhibitors

Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per year in the Americas. Current medical therapy for CD has low efficacy in the chronic phase of the disease and serious adverse effects; therefore, it is necessary to search for new pharmacological treatments. In this...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Herrera-Mayorga, Verónica, Lara-Ramírez, Edgar E., Chacón-Vargas, Karla F., Aguirre-Alvarado, Charmina, Rodríguez-Páez, Lorena, Alcántara-Farfán, Verónica, Cordero-Martínez, Joaquín, Nogueda-Torres, Benjamín, Reyes-Espinosa, Francisco, Bocanegra-García, Virgilio, Rivera, Gildardo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479639/
https://ncbi.nlm.nih.gov/pubmed/30970549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071742
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