Structure-Based Virtual Screening and In Vitro Evaluation of New Trypanosoma cruzi Cruzain Inhibitors

Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per year in the Americas. Current medical therapy for CD has low efficacy in the chronic phase of the disease and serious adverse effects; therefore, it is necessary to search for new pharmacological treatments. In this...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Herrera-Mayorga, Verónica, Lara-Ramírez, Edgar E., Chacón-Vargas, Karla F., Aguirre-Alvarado, Charmina, Rodríguez-Páez, Lorena, Alcántara-Farfán, Verónica, Cordero-Martínez, Joaquín, Nogueda-Torres, Benjamín, Reyes-Espinosa, Francisco, Bocanegra-García, Virgilio, Rivera, Gildardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479639/
https://ncbi.nlm.nih.gov/pubmed/30970549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071742
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