Structure-Based Virtual Screening and In Vitro Evaluation of New Trypanosoma cruzi Cruzain Inhibitors

Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per year in the Americas. Current medical therapy for CD has low efficacy in the chronic phase of the disease and serious adverse effects; therefore, it is necessary to search for new pharmacological treatments. In this...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Herrera-Mayorga, Verónica, Lara-Ramírez, Edgar E., Chacón-Vargas, Karla F., Aguirre-Alvarado, Charmina, Rodríguez-Páez, Lorena, Alcántara-Farfán, Verónica, Cordero-Martínez, Joaquín, Nogueda-Torres, Benjamín, Reyes-Espinosa, Francisco, Bocanegra-García, Virgilio, Rivera, Gildardo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479639/
https://ncbi.nlm.nih.gov/pubmed/30970549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071742
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