LGG-08. PROTEOGENOMICS REVEALS TWO DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA tumorigenesis. While five-year overall survival rates exceed 95%, tumor recurrence constitutes a major clinical challenge in incompletely resected tumors de...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Göbbles, Sarah, Stefanski, Anja, Stühler, Kai, Roque, Lucia, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
Low Grade Glioma
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477412/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.151
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