LGG-38. PROTEOGENOMICS REVEALS THREE DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA formation. While five-year overall survival rates exceed 95%, incompletely resected tumors recur frequently despite treatment. Therefore, we used proteogeno...

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Publicado en:Neuro Oncol
Autores principales: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Stefanski, Anja, Roque, Lucia, Stühler, Kai, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012590/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.379
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