LGG-38. PROTEOGENOMICS REVEALS THREE DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA formation. While five-year overall survival rates exceed 95%, incompletely resected tumors recur frequently despite treatment. Therefore, we used proteogeno...

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Publicat a:Neuro Oncol
Autors principals: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Stefanski, Anja, Roque, Lucia, Stühler, Kai, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012590/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.379
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