LGG-10. PROTEOGENOMICS DISCRIMINATES PEDIATRIC AND ADULT PILOCYTIC ASTROCYTOMA AS DISTINCT BIOLOGICAL ENTITIES

Pilocytic astrocytoma (PA) is a well-circumscribed, slow growing, low-grade brain tumor predominantly affecting children and considered a single-pathway disease with activation of MAPK signaling, typically driven by BRAF alterations. While five-year overall survival rates exceed 95%, incompletely re...

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Published in:Neuro Oncol
Main Authors: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Stefanski, Anja, Stühler, Kai, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475098/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.143
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