LGG-08. PROTEOGENOMICS REVEALS TWO DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA tumorigenesis. While five-year overall survival rates exceed 95%, tumor recurrence constitutes a major clinical challenge in incompletely resected tumors de...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Göbbles, Sarah, Stefanski, Anja, Stühler, Kai, Roque, Lucia, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Low Grade Glioma
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477412/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.151
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