LGG-08. PROTEOGENOMICS REVEALS TWO DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA tumorigenesis. While five-year overall survival rates exceed 95%, tumor recurrence constitutes a major clinical challenge in incompletely resected tumors de...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Göbbles, Sarah, Stefanski, Anja, Stühler, Kai, Roque, Lucia, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Low Grade Glioma
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477412/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.151
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