LGG-08. PROTEOGENOMICS REVEALS TWO DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. Aberrant MAPK signaling, typically mediated by BRAF alterations, drives PA tumorigenesis. While five-year overall survival rates exceed 95%, tumor recurrence constitutes a major clinical challenge in incompletely resected tumors de...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Pauck, David, Marquardt, Viktoria, Meyer, Frauke, Göbbles, Sarah, Stefanski, Anja, Stühler, Kai, Roque, Lucia, Borkhardt, Arndt, Reifenberger, Guido, Faria, Cláudia, Remke, Marc
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Low Grade Glioma
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477412/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.151
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