DIPG-34. PRECLINICAL PRECISION TESTING OF PNOC003 BIOPSY DERIVED MODELS OF DIPG

RATIONALE: One of the major hurdles in developing effective treatment for children with DIPG includes the lack of extensive combinatorial studies targeting major driver oncogenic pathways. Combination of H3K27M and TP53 mutations are found in over 50% of DIPG tumors, however, there is a lack of effe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Panditharatna, Eshini, Yadavili, Sridevi, Yang, Xiaodong, Zhang, Jie, Truffaux, Nathalene, Zhai, Yuying, Kambhampati, Madhuri, Zhang, Bo, Zhu, Yuankun, Jain, Payal, Kline, Cassie, Packer, Roger J, Prados, Michael, Gupta, Nalin, Resnick, Adam, Mueller, Sabine, Nazarian, Javad
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
Diffuse Intrinsic Pontine Glioma (DIPG)
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477401/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.055
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