GENE-18. PAN-OMIC ANALYSIS OF DIFFUSE INTRINSIC PONTINE GLIOMA FROM CHILDREN ENROLLED IN THE PNOC003 PRECISION MEDICINE TRIAL IDENTIFIES OPPORTUNITIES AND CHALLENGES IN CLINICAL IMPLEMENTATION OF A MULTI-OMICS SEQUENCING APPROACH

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is an infiltrative, inoperable midline tumor with devastating outcomes. We have recently completed a prospective clinical trial for children and young adults with newly diagnosed DIPG that included clinical whole exome sequencing (WES) and RNA sequ...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jain, Payal, Mueller, Sabine, Liang, Winnie S, Panditharatna, Eshini, Zhang, Bo, Zhu, Yuankun, Kambhampati, Madhuri, Kline, Cassie, Kilburn, Lindsay, Gupta, Nalin, Yang, Xiaodong, Nazemi, Kellie, Magge, Suresh N, Crawford, John, Banerjee, Anu, Packer, Roger J, Roos, Alison, Philips, Joanna, Solomon, David, Molinaro, Annette, Yadavili, Sridevi, Kuhn, John, Byron, Sara A, Prados, Michael, Nazarian, Javad, Berens, Michael, Resnick, Adam C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Genetics/Epigentics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477407/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.089
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