DIPG-34. PRECLINICAL PRECISION TESTING OF PNOC003 BIOPSY DERIVED MODELS OF DIPG

RATIONALE: One of the major hurdles in developing effective treatment for children with DIPG includes the lack of extensive combinatorial studies targeting major driver oncogenic pathways. Combination of H3K27M and TP53 mutations are found in over 50% of DIPG tumors, however, there is a lack of effe...

Full description

Saved in:
Bibliographic Details
Published in:Neuro Oncol
Main Authors: Panditharatna, Eshini, Yadavili, Sridevi, Yang, Xiaodong, Zhang, Jie, Truffaux, Nathalene, Zhai, Yuying, Kambhampati, Madhuri, Zhang, Bo, Zhu, Yuankun, Jain, Payal, Kline, Cassie, Packer, Roger J, Prados, Michael, Gupta, Nalin, Resnick, Adam, Mueller, Sabine, Nazarian, Javad
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Diffuse Intrinsic Pontine Glioma (DIPG)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477401/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.055
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items