DIPG-15. PNOC-003: CLINICAL IMPACT OF A PRECISION MEDICINE STRATEGY FOR CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA

OBJECTIVE: We evaluated the impact on overall survival at 12 months (OS12) of a personalized therapy plan based on tumor/germline whole exome (WES) and tumor RNA sequencing (RNAseq) of diffuse intrinsic pontine glioma (DIPG). METHODS: We enrolled newly diagnosed DIPG patients ≤ 25 years of age. Tumo...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mueller, Sabine, Kline, Cassie, Kilburn, Lindsay, Liang, Winnie S, Jain, Payal, Gupta, Nalin, Panditharatna, Eshini, Nazemi, Kellie, Magge, Suresh N, Crawford, John, Banerjee, Anu, Packer, Roger, Roos, Alison, Zhang, Bo, Zhu, Yuankun, Aboian, Mariam, Tamrazi, Benita, Philips, Joanna, Solomon, David, Molinaro, Annette, Kuhn, John, Byron, Sara A, Nazarian, Javad, Resnick, Adam, Berens, Michael, Prados, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Diffuse Intrinsic Pontine Glioma (DIPG)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.036
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