DIPG-15. PNOC-003: CLINICAL IMPACT OF A PRECISION MEDICINE STRATEGY FOR CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA

OBJECTIVE: We evaluated the impact on overall survival at 12 months (OS12) of a personalized therapy plan based on tumor/germline whole exome (WES) and tumor RNA sequencing (RNAseq) of diffuse intrinsic pontine glioma (DIPG). METHODS: We enrolled newly diagnosed DIPG patients ≤ 25 years of age. Tumo...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Mueller, Sabine, Kline, Cassie, Kilburn, Lindsay, Liang, Winnie S, Jain, Payal, Gupta, Nalin, Panditharatna, Eshini, Nazemi, Kellie, Magge, Suresh N, Crawford, John, Banerjee, Anu, Packer, Roger, Roos, Alison, Zhang, Bo, Zhu, Yuankun, Aboian, Mariam, Tamrazi, Benita, Philips, Joanna, Solomon, David, Molinaro, Annette, Kuhn, John, Byron, Sara A, Nazarian, Javad, Resnick, Adam, Berens, Michael, Prados, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Diffuse Intrinsic Pontine Glioma (DIPG)
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.036
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